CRESTOR LDL-C lipid lowering efficacy

It is generally accepted that the key driver in the prevention of cardiovascular disease is likely to be LDL-C reduction37-38.
Epidemiology and intervention studies have shown that a 1% decrease in LDL-C reduces CHD risk by 1%.40

CRESTOR has proven its capability in reducing LDL-C in an extensive clinical trial program:

• CRESTOR is the most effective statin at lowering LDL-C 1-29
• • highly effective reductions in LDL-C of up to 63% 29
    
  • superior LDL-C lowering versus atorvastatin in 25 comparative studies involving >20,000 patients 1-15, 18-28
    
• CRESTOR 10 mg can cut LDL-C in half 5,8,23,29 and produces:
• • greater LDL-C reductions than the same and some higher doses of other statins 1-15, 18-27 
    
  • greater LDL-C reductions than atorvastatin 10 and 20 mg 2, 13-15
    
  • greater achievement of LDL-C goals than commonly prescribed doses of other statins 1-5, 14, 21, 22, 30-32, avoiding the need to titrate to higher doses .